What is RE-GEN™ Bioactive EndoSealer made of?

Calcium aluminate based cement, Bioglass and Zirconium oxide as radiopacifier

Why calcium aluminate?

Compared to other sealers on the market that typically utilize calcium silicate (Portland cement), calcium aluminate has significant advantages including increased strength, increased acid resistance, and quicker setting, all important attributes for an endodontic sealer. Calcium aluminate is significantly more expensive than calcium silicate (Portland cement), but the added benefits are totally worth the extra cost to Vista Apex to provide a high quality endodontic sealer!

What makes it bioactive?

RE-GEN™ Bioactive EndoSealer contains bioglass that promotes remineralization of hydroxyapatite through calcium (Ca) and phosphate (PO4) ion release. Through the release of these ions, remineralization of dentin within the root canal occurs thereby strengthening the dentin and promoting longevity of the treated tooth.

RE-GEN™ Bioactive Endosealer is a hydraulic cement which means it uses moisture naturally present in the tooth to initiate and complete its setting reaction.

What makes it highly antibacterial?

Hydroxide (OH) is released as part of the cement setting process which gives the sealer an alkaline pH (~12).

Is RE-GEN™ Bioactive EndoSealer non-staining?

Yes, it is non-staining because it contains zirconium oxide as the radiopacifier which does not cause staining.

How much material do I get?

(1) 2 g RE-GEN™ Bioactive Endosealer sealant in our ergonomically shaped syringe for easy extrusion.

What kind of tips are included with this kit?

Each sealer kit comes with 20 of Vista Apex’s patented MST Visco-Tips™. These tips have been engineered to reduce waste (87% compared to other sealer tips) making each syringe of RE-GEN™ Bioactive EndoSealer go further and putting money back in your pocket.

What is the set time?

Material will set in ≤ 1 hour (however, set time is dependent on the level of moisture present in the tooth).

What is the work time?

Greater than 4 hours. Setting will begin in the presence of moisture.

Do I need to completely dry the canals before applying RE-GEN™ Bioactive EndoSealer?

No, it is not necessary. Any excess irrigants or moisture from surrounding tissues should be removed with absorbent points but moisture is used to set the sealer.

What brand of gutta percha can I use with RE-GEN™ Bioactive EndoSealer?

RE-GEN™ Bioactive EndoSealer is compatible with all gutta percha, although reference to the gutta percha’s instructions for use should always be referenced to make sure there aren’t any constraints.

Will the RE-GEN™ Bioactive EndoSealer reabsorb in the case of material extrusion into the perapical area?

Our material is biocompatible and was subjected to significant biocompatibility testing to ISO 10993 standards as part of the FDA’s 510(k) clearance of the product. Any incidental apical extrusion will not result in a significant inflammatory response although apical extrusion should be minimized as much as possible just like all other endodontic materials and sealers.

Can RE-GEN™ Bioactive EndoSealer be retreatable?

Yes, teeth treated with RE-GEN™ Bioactive EndoSealer can be retreated following conventional techniques.

What makes RE-GEN™ Bioactive EndoSealer different than other bioceramic sealers?

RE-GEN™ Bioactive Endosealer incorporates Vista Apex’s RE-GEN™ technology that leverages over 50 years of medical and orthopedic clinical use for remineralization of hydroxyapatite materials (e.g. bone and teeth). The formulation has been specifically engineered to incorporate all the clinical advantages desired in an endodontic sealer including bioactivity, high radiopacity and alkalinity, quick set time, high flowability, and low solubility.

Can I throw away the desiccant pack in the foil pouch?

The desiccant pack is to absorb any moisture trapped inside the foil pouch. Since the sealer uses moisture to set, any excess moisture in the foil pouch may prematurely set the material in the syringe prior to use. Once the syringe is empty, all product components can be disposed in accordance with regional waste requirements.

What is the shelf life of RE-GEN™ Bioactive EndoSealer?

Two (2) years from the manufacturer date.

How do I store the sealer?

Place sealer back into the resealable foil pouch and keep the provided desiccant pack in the foil pouch. Place the foil pouch in a dry and temperature-controlled environment in accordance with the packaging.

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